Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266538 | 0.92 | SOS1 (0.34) | SOS1SCN9A | |
| SCHEMBL12921307 | 0.91 | — | — | |
| SCHEMBL12921209 | 0.88 | SOS1 (0.37) | SOS1 | |
| SCHEMBL8053421 | 0.88 | DRD2 (0.36) | — | |
| SCHEMBL8060129 | 0.88 | CDK1 (0.36) | — | |
| SCHEMBL12921221 | 0.87 | KDM4E (0.36) | SCN9A | |
| SCHEMBL8058982 | 0.85 | DRD3 (0.37) | SCN9A | |
| SCHEMBL12921309 | 0.85 | DRD2 (0.33) | — | |
| SCHEMBL8056390 | 0.85 | DRD2 (0.36) | SOS1 | |
| SCHEMBL373806 | 0.85 | TP53 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610258-B1 | Substituted piperidino dihydrothieno pyrimidines | BOEHRINGER INGELHEIM INT (DE) | 2014-08-27 | — | — | EP | disclosed |