Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806506 | 1.00 | SRD5A1 (0.49) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL15978289 | 0.90 | SRD5A1 (0.44) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL15978419 | 0.82 | CYP3A4 (0.43) | NR1H2NR1H3 | |
| SCHEMBL15978295 | 0.81 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL806508 | 0.81 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL15978303 | 0.81 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL806727 | 0.81 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL15978308 | 0.79 | POLA1 (0.63) | NR1H2NR1H3LMNA | |
| SCHEMBL3096973 | 0.77 | SRD5A1 (0.55) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL14456321 | 0.77 | SRD5A1 (0.55) | SRD5A1NR1H2NR1H3LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | WEE1, WEE2, NOTUM | SRD5A1 2114/4885NR1H2 1557/4885NR1H3 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.