Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978303 | 1.00 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL15978295 | 0.81 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL806506 | 0.81 | SRD5A1 (0.49) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL806727 | 0.81 | SRD5A1 (0.46) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL15978294 | 0.81 | SRD5A1 (0.49) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL3091289 | 0.76 | NR1H2 (0.43) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL14456321 | 0.74 | SRD5A1 (0.55) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL3096973 | 0.74 | SRD5A1 (0.55) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL3091593 | 0.74 | LMNA (0.50) | SRD5A1NR1H2NR1H3LMNATDP1 | |
| SCHEMBL14695169 | 0.74 | LMNA (0.50) | SRD5A1NR1H2NR1H3LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037069-A2 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-03-22 | — | — | WO | disclosed |