Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634941 | 0.88 | TSHR (0.39) | TSHRALDH1A1OPRM1 | |
| SCHEMBL16107215 | 0.88 | TSHR (0.43) | TSHRALDH1A1OPRM1 | |
| SCHEMBL25125852 | 0.88 | TSHR (0.43) | TSHRALDH1A1OPRM1 | |
| SCHEMBL1817041 | 0.85 | TSHR (0.41) | TSHRALDH1A1OPRM1 | |
| SCHEMBL29287268 | 0.85 | TSHR (0.41) | TSHRALDH1A1OPRM1 | |
| SCHEMBL11742763 | 0.85 | TSHR (0.40) | TSHRALDH1A1OPRM1FAAH | |
| SCHEMBL10397989 | 0.82 | TSHR (0.41) | TSHRALDH1A1FAAH | |
| SCHEMBL9407355 | 0.81 | LMNA (0.44) | TSHRALDH1A1 | |
| SCHEMBL10795533 | 0.80 | TSHR (0.43) | TSHRALDH1A1OPRM1FAAH | |
| SCHEMBL598598 | 0.80 | TSHR (0.43) | TSHRALDH1A1OPRM1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | WEE1, WEE2, NOTUM | TSHR 2271/4885ALDH1A1 1556/4885OPRM1 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.