Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18912020 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL10224281 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL23638525 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL21941232 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL750920 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL8350565 | 0.71 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL14424533 | 0.70 | NPSR1 (0.57) | KDM4EALDH1A1SMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL252699 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL252260 | 0.69 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2CYP2C9KMT2A | |
| SCHEMBL24862850 | 0.68 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243292-A1 | SUBSITUTED 2-(CHROMAN-6-YLOXYL)-THIAZOLES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243292-A1 | SUBSITUTED 2-(CHROMAN-6-YLOXYL)-THIAZOLES AND THEIR USE AS PHARMACEUTICALS | RYR2, CACNA1E, SLC8B1 | KDM4E 3167/4885ALDH1A1 2007/4885SMN1; SMN2 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.