SLC8B1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL869274	1.00	1/20
SCHEMBL31071906	1.00	1/20
SCHEMBL10044117	0.79	1/20
SCHEMBL10929981	0.77	1/20
SCHEMBL7196864	0.61	1/20
SCHEMBL10926019	0.60	1/20
SCHEMBL8117192	0.60	1/20
SCHEMBL28355878	0.56	1/20
SCHEMBL5435436	0.56	1/20
SCHEMBL10929004	0.56	1/20
SCHEMBL11085842	0.55	1/20
SCHEMBL4110833	0.55	1/20
SCHEMBL4110835	0.55	1/20
SCHEMBL4110842	0.55	1/20
SCHEMBL4371172	0.55	1/20
SCHEMBL13981274	0.52	1/20
SCHEMBL4219649	0.51	1/20
SCHEMBL5177430	0.50	1/20
SCHEMBL8116269	0.50	1/20
SCHEMBL11080868	0.50	1/20

Clinical trials — most relevant to SLC8B1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Magnesium Administration in Liver Transplantation and Reperfusion Injury	PHASE4	COMPLETED
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)	PHASE3	COMPLETED
Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression	PHASE2/PHASE3	NOT_YET_RECRUITING
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	PHASE2	ACTIVE_NOT_RECRUITING
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Treatment of Iron Overload With Deferasirox (Exjade) in Hereditary Hemochromatosis and Myelodysplastic Syndrome	PHASE2	WITHDRAWN
A Phase I, Open-Labeled, Single-Arm, Dose Escalation, Clinical and Pharmacology Study of Dichloroacetate (DCA) in Patients With Recurrent and/or Metastatic Solid Tumours	PHASE1	COMPLETED
Oxalate and Citrate in Humans - Response to Citrate	nan	RECRUITING
Predicting Pancreatic Necrosis Using mitDNA	nan	UNKNOWN
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy	nan	COMPLETED
Prevalence and Risk Factors of Nephrocalcinosis in Children at Sohag University Hospital	nan	UNKNOWN
Lithium Countertransport and Blood Pressure In CARDIA and TOMHS	nan	COMPLETED
Expression of SLC25A48 in Chronic Obstructive Pulmonary Disease	nan	NOT_YET_RECRUITING
Sodium Transport: Genetics and Hypertension	nan	COMPLETED
The Energetic Origin of Neurodegeneration in MS	nan	COMPLETED
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)	nan	COMPLETED
Genetic and Environmental Determinants of Hypertension	nan	COMPLETED
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study)	nan	COMPLETED
Cardiovascular Effects of Empagliflozine	nan	UNKNOWN
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts	nan	COMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle	nan	COMPLETED
Triheptanoin (UX007) to Treat Citrate Transporter Deficiency	nan	NO_LONGER_AVAILABLE
Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes	nan	RECRUITING
The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2	nan	UNKNOWN
POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS	nan	NOT_YET_RECRUITING
Observational Study of the Impact of Genetic Testing on Healthcare Decisions and Care in Interventional Pain Management	nan	UNKNOWN
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome	nan	UNKNOWN
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders	nan	UNKNOWN
Transgenerational Metabolic-Immune Biomarkers of Neurological and Neurodevelopmental Disorders	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a SLC8B1 binder may also engage these)

Protein	Name	Similarity
Q6AXS0	—	1.000	Q6AXS0 →
F1NXU8	—	1.000	F1NXU8 →
Q925Q3	—	0.995	Q925Q3 →
Q9LJI2	—	0.969	Q9LJI2 →
Q921R8	—	0.969	Q921R8 →
Q9SYG9	—	0.966	Q9SYG9 →
Q8C261	—	0.966	Q8C261 →
Q96GZ6	—	0.965	Q96GZ6 →
Q3SWT5	—	0.962	Q3SWT5 →
Q9TT16	—	0.961	Q9TT16 →
P51800	—	0.960	P51800 →
Q80SU6	—	0.960	Q80SU6 →
SLC34A1	Sodium-dependent phosphate transport protein 2A	0.959	landscape →
P51797	—	0.958	P51797 →
Q3TD49	—	0.958	Q3TD49 →
O35454	—	0.958	O35454 →
A2BFP5	—	0.958	A2BFP5 →
Q71RS6	—	0.958	Q71RS6 →
P51803	—	0.958	P51803 →
Q8K4R8	—	0.958	Q8K4R8 →
Q06393	—	0.957	Q06393 →
Q9WUB6	—	0.957	Q9WUB6 →
P51801	—	0.957	P51801 →
O97704	—	0.957	O97704 →
Q945S5	—	0.957	Q945S5 →
Q7G7C7	—	0.957	Q7G7C7 →
Q5KQN0	—	0.957	Q5KQN0 →
P51802	—	0.957	P51802 →
Q5TKG3	—	0.956	Q5TKG3 →
Q49SH1	—	0.956	Q49SH1 →