Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 0.94 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065914 | 0.97 | ADORA2B (1.00) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL4397341 | 0.84 | ADORA2B (0.95) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4405247 | 0.83 | ADORA2B (1.00) | ADORA2B | |
| SCHEMBL1946601 | 0.82 | ADORA2A (1.00) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL1946456 | 0.82 | ADORA2B (0.74) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL1945002 | 0.82 | ADORA2B (0.84) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL15988336 | 0.82 | ADORA2B (0.73) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL1065915 | 0.81 | ADORA2B (0.83) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4399842 | 0.81 | ADORA2B (1.00) | ADORA2B | |
| SCHEMBL1065130 | 0.81 | ADORA2B (1.00) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268641-B1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT LTD (IN) | 2014-09-03 | — | — | EP | claimed |