SCHEMBL15988293

SCHEMBL15988293

CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OC[C@@H]4CCCN4OC(=O)OC(C)(C)C)cc3)oc2c1

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15988261 1.00 GPR119 (0.80) GPR119
SCHEMBL2586947 0.89 GPR119 (1.00) GPR119
SCHEMBL2587588 0.89 GPR119 (1.00) GPR119
SCHEMBL15988171 0.88 GPR119 (0.82) GPR119
SCHEMBL14759035 0.86 GPR119 (0.84) GPR119
SCHEMBL14759067 0.86 GPR119 (0.84) GPR119
SCHEMBL2582136 0.86 GPR119 (1.00) GPR119
SCHEMBL2592501 0.84 GPR119 (1.00) GPR119
SCHEMBL2587600 0.84 GPR119 (1.00) GPR119
SCHEMBL2592301 0.84 GPR119 (1.00) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2566864-B1 PYRIDAZINONES AS GPR119 AGONISTS BOEHRINGER INGELHEIM INT (DE) 2014-09-03 EP claimed