Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 15/20 | 0.56 |
| ▸ | WNT3A | P56704 | 15/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988785 | 0.90 | CTNNB1 (0.58) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL7365546 | 0.85 | SLC22A6 (0.60) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL15980074 | 0.78 | CTNNB1 (0.62) | CTNNB1WNT3AALDH1A1 | |
| SCHEMBL30089582 | 0.77 | CTNNB1 (0.75) | CTNNB1WNT3AGAA | |
| SCHEMBL31134778 | 0.76 | HTT (0.65) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL5190466 | 0.76 | HTT (0.65) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL17350715 | 0.76 | SLC22A6 (0.62) | CTNNB1WNT3AMEN1KMT2AGAA | |
| SCHEMBL3811067 | 0.74 | SLC22A6 (0.64) | CTNNB1WNT3AMEN1KMT2AGAA | |
| SCHEMBL29595420 | 0.74 | SLC22A6 (0.64) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| SCHEMBL30266750 | 0.74 | SLC22A6 (0.64) | CTNNB1WNT3AMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014130869-A1 | GAMMA-DIKETONES AS WNT/BETA -CATENIN SIGNALING PATHWAY ACTIVATORS | SAMUMED, LLC (US) | 2014-08-28 | — | — | WO | disclosed |