SCHEMBL15988985

SCHEMBL15988985

B[C@@H]1O[C@H](CCP(=O)(OCC)OCC)C[C@@H]1CC(C)(C)[Si](C)(C)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17577486 0.76 PPARD (0.40) PPARD
SCHEMBL15988983 0.75
SCHEMBL19879917 0.74 PPARD (0.30) PPARD
SCHEMBL15988953 0.73
SCHEMBL19750956 0.68
SCHEMBL19774555 0.61 PPARD (0.40) PPARD
SCHEMBL30186533 0.60 PPARD (0.39) PPARD
SCHEMBL1592913 0.60 PPARD (0.50) PPARD
SCHEMBL17576558 0.58
SCHEMBL30186704 0.58 PPARD (0.37) PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2958998-B1 SHORT INTERFERING NUCLEIC ACID (SINA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE SIRNA THERAPEUTICS INC (US) 2017-12-27 EP disclosed
WO-2014130607-A1 SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE SIRNA THERAPEUTICS, INC. (US) 2014-08-28 WO disclosed