Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988985 | 0.76 | PPARD (0.32) | PPARD | |
| SCHEMBL19879917 | 0.75 | PPARD (0.30) | PPARD | |
| SCHEMBL17577479 | 0.74 | POLB (0.31) | — | |
| SCHEMBL17159586 | 0.72 | — | — | |
| SCHEMBL15279168 | 0.70 | FBP1 (0.46) | — | |
| SCHEMBL19774555 | 0.69 | PPARD (0.40) | PPARDTSHR | |
| SCHEMBL17577485 | 0.69 | — | — | |
| SCHEMBL25758493 | 0.68 | PPARD (0.43) | PPARDTSHR | |
| SCHEMBL1592913 | 0.67 | PPARD (0.50) | PPARDTSHR | |
| SCHEMBL17577492 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160068837-A1 | SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE | SIRNA THERAPEUTICS, INC. (US) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068837-A1 | SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE | NSUN2, AGO2, NSUN3 | PPARD 4875/4885TSHR 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.