SCHEMBL1600172

SCHEMBL1600172

Nc1ccc2c(N)c(N)ccc2c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 2/20 0.44
LMNA P02545 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
HTT P42858 1/20 0.44
BLM P54132 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP3A4 P08684 8/20 0.37
TDP1 Q9NUW8 6/20 0.37
ALDH1A1 P00352 6/20 0.37
TSHR P16473 5/20 0.37
HSD17B10 Q99714 4/20 0.37
HPGD P15428 2/20 0.37
CD44 P16070 1/20 0.36
ALOX15 P16050 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9797243 0.96 KMT2A (0.42) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL10867763 0.85 TDP1 (0.39) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL2446500 0.83 ALDH1A1 (0.68) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL30884128 0.79 CYP3A4 (0.43) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL135806 0.79 CYP3A4 (0.43) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL175362 0.77 HPRT1 (0.64) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL5249230 0.77 MEN1 (0.41) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL7299900 0.77 MEN1 (0.41) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL10432943 0.77 NR4A2 (0.64) MEN1KMT2AMAPTLMNAHSP90AA1
SCHEMBL5249233 0.77 CYP1A2 (0.59) MEN1KMT2AMAPTLMNAHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096284-B organic compounds with two-photon absorption characteristic and preparation method and application thereof 山东师范大学 2020-01-31 CN claimed
CN-109096284-A A kind of organic compound and its preparation method and application with two-Photon Absorption Properties 山东师范大学 2018-12-28 CN claimed
CN-105709612-A Molecule assembling-based preparation method of polypyrrolone/aromatic polyamide composite membrane 江西师范大学 2016-06-29 CN claimed
CN-105713213-A Molecule assembling-based preparation method of polypyrrolone membrane 江西师范大学 2016-06-29 CN claimed
CN-105714406-A Molecule assembling-based preparation method of polypyrrolone/nylon composite fiber composite material 江西师范大学 2016-06-29 CN claimed
CN-105383347-A High-performance TPE (Thermal Plastic Elastomer) vehicle foot pad and preparation method thereof ANHUI XIONGYA PLASTIC TECH CO LTD 2016-03-09 CN claimed
CN-105199293-A Environment-friendly and high-performance TPE (thermal plastic elastomers) food bottle cap and preparation method thereof ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2015-12-30 CN claimed
CN-105111657-A High-strength high-antibacterial-property TPE (thermoplastic elastomer) shock-absorption insole and preparation method thereof ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2015-12-02 CN claimed
CN-103724630-B The synthetic method of block type sulfonated polyimide-polybenzimidazole proton exchange membrane material TONGJI UNIVERSITY (CN) 2015-11-25 CN claimed
CN-105001581-A TPE composition and high-performance sealing material obtained from same ANHUI XIONGYA PLASTIC TECHNOLOGY CO LTD 2015-10-28 CN claimed
CN-102863620-A Preparation method of aromatic polybenzimidazole SHANGHAI DIAIBI CHEMICAL TECHNOLOGY CO LTD 2013-01-09 CN claimed
US-7754846-B2 Thermal processes for increasing polyareneazole inherent viscosities E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-13 US claimed
US-7704422-B2 pyrolyzing the consolidated disks which contains polyimide and polybenzimidazole powder, in an inert atmosphere or carbon dioxide to form a monolithic porous carbon doped with metals; low cost production; high surface area, high pore volume, high surface activity, good mechanical properties ELECTROMATERIALS, INC. (US) 2010-04-27 US claimed
CN-101006007-A Processes for producing monolithic porous carbon disks from aromatic organic precursors JING WANG (US) 2007-07-25 CN claimed
US-20070100120-A1 Thermal processes for increasing polyareneazole inherent viscosities E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-03 US claimed
WO-2006105227-A1 THERMAL PROCESSES FOR INCREASING POLYARENEAZOLE INHERENT VISCOSITIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-10-05 WO claimed
CN-1250609-C Benzimidazole with sulfonate as side group and benzoxaazole copolymer and its preparation UNIV SHANGHAI JIAOTONG (CN) 2006-04-12 CN claimed
US-20060033226-A1 Processes for producing monolithic porous carbon disks from aromatic organic precursors ELECTROMATERIALS, INC. 2006-02-16 US claimed
US-20060033225-A1 pyrolyzing the consolidated disks which contains polyimide and polybenzimidazole powder, in an inert atmosphere or carbon dioxide to form a monolithic porous carbon doped with metals; low cost production; high surface area, high pore volume, high surface activity, good mechanical properties ELECTROMATERIALS, INC. 2006-02-16 US claimed
CN-1583831-A Benzimidazole with sulfonate as side group and benzoxaazole copolymer and its preparation UNIV SHANGHAI COMMUNICATION (CN) 2005-02-23 CN claimed