Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | HINT1 | P49773 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 5/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16004522 | 1.00 | POLB (0.51) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20782763 | 0.88 | POLB (0.58) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL14750407 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL21609617 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL14750417 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924348 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL21609618 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924553 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20924422 | 0.86 | POLB (0.54) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL22053473 | 0.85 | POLB (0.67) | POLBFUT5P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014134355-A1 | DRUG COMBINATIONS | ASTEX PHARMACEUTICALS, INC. (US) | 2014-09-04 | — | — | WO | disclosed |