Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.54 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20325223 | 0.94 | TERT (0.53) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL21540009 | 0.94 | TERT (0.53) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20324868 | 0.94 | TERT (0.53) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20782764 | 0.94 | TERT (0.53) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20324811 | 0.94 | POLB (0.52) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL21540026 | 0.93 | POLB (0.53) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20326987 | 0.92 | POLB (0.51) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL20325274 | 0.92 | POLB (0.50) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL29324598 | 0.91 | POLB (0.49) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL23679395 | 0.91 | POLB (0.49) | POLBFUT5P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079261-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019074887-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-18 | — | — | WO | disclosed |
| WO-2019046496-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019046500-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |
| WO-2019046498-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |