Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 10/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386164 | 0.88 | MEN1 (0.36) | LGMNMEN1KMT2AMAPTALDH1A1 | |
| Iodide SCHEMBL13386168 | 0.87 | MEN1 (0.36) | LGMNMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL2594059 | 0.86 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13386157 | 0.84 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL13386162 | 0.82 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL13386325 | 0.82 | MEN1 (0.36) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL15925819 | 0.82 | MAPT (0.45) | LGMNMEN1KMT2AMAPTALDH1A1 | |
| Iodide SCHEMBL13386230 | 0.81 | MEN1 (0.36) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Iodide SCHEMBL13386326 | 0.81 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL16004713 | 0.81 | MAPT (0.39) | LGMNMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828986-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-09-09 | — | — | US | claimed |