Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LGMN | Q99538 | 3/20 | 0.38 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13386452 | 0.99 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1NPSR1LGMN | |
| SCHEMBL16004704 | 0.96 | LGMN (0.40) | MAPTSMN1; SMN2ALDH1A1LGMNPRKDC | |
| Hydrochloric Acid SCHEMBL13386331 | 0.95 | LGMN (0.40) | MAPTSMN1; SMN2ALDH1A1LGMNPRKDC | |
| SCHEMBL16004697 | 0.85 | SLC2A1 (0.37) | MAPTSMN1; SMN2ALDH1A1LGMNPRKDC | |
| Hydrochloric Acid SCHEMBL13386137 | 0.84 | SLC2A1 (0.37) | MAPTSMN1; SMN2ALDH1A1LGMNPRKDC | |
| Hydrochloric Acid SCHEMBL13386103 | 0.83 | KDM4E (0.37) | MAPTSMN1; SMN2ALDH1A1LGMNNPC1 | |
| SCHEMBL13386284 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2ALDH1A1LGMNNPC1 | |
| SCHEMBL13386113 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1NPSR1LGMN | |
| SCHEMBL13386249 | 0.79 | LGMN (0.38) | MAPTSMN1; SMN2ALDH1A1LGMNPRKDC | |
| SCHEMBL13386292 | 0.79 | LGMN (0.38) | MAPTSMN1; SMN2ALDH1A1LGMNPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828986-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-09-09 | — | — | US | claimed |