Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18785798 | 0.82 | ELANE (0.56) | ELANE | |
| SCHEMBL11790413 | 0.79 | KMT2A (0.57) | ELANEKMT2AMAPTMEN1CYP11B1 | |
| SCHEMBL7866641 | 0.79 | KMT2A (0.57) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL29250860 | 0.78 | KMT2A (0.49) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL22369614 | 0.78 | ELANE (0.86) | ELANE | |
| SCHEMBL9413732 | 0.78 | KMT2A (0.55) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL2525492 | 0.78 | KMT2A (0.55) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL30566578 | 0.78 | KMT2A (0.55) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL9517194 | 0.76 | KMT2A (0.54) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL16005701 | 0.75 | KMT2A (0.54) | ELANEKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | PAH, DDT, NISCH | ELANE 468/4885KMT2A 760/4885MAPT 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.