Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790413 | 0.88 | KMT2A (0.57) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL2525492 | 0.82 | KMT2A (0.55) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL30566578 | 0.82 | KMT2A (0.55) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL9413732 | 0.82 | KMT2A (0.55) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL9517194 | 0.81 | KMT2A (0.54) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL21050084 | 0.80 | KMT2A (0.67) | KMT2AMAPTMEN1TDP1LMNA | |
| SCHEMBL16005606 | 0.79 | ELANE (0.56) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL27773944 | 0.79 | KMT2A (0.57) | KMT2AMAPTMEN1CYP11B1CYP11B2 | |
| SCHEMBL10646167 | 0.79 | ALDH1A1 (0.38) | KMT2AMAPTMEN1TDP1LMNA | |
| SCHEMBL377118 | 0.79 | P4HTM (0.48) | KMT2AMAPTCYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2551265-B2 | Novel process for the preparation of 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of etoricoxib. | F I S - FABBRICA ITALIANA SINTETICI S P A (IT) | 2017-09-13 | — | — | EP | claimed |
| EP-2551265-B1 | Novel process for the preparation of 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of etoricoxib. | ITALIANA SINT SPA (IT) | 2015-01-07 | — | — | EP | claimed |
| EP-0730597-B1 | HETEROCYCLIC ESTERS OF RAPAMYCIN AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN HOME PROD (US) | 2001-03-07 | — | — | EP | claimed |
| EP-0300461-B1 | Aromatic heterocyclic peroxyacids | AUSIMONT SPA (IT) | 1994-01-12 | — | — | EP | claimed |
| EP-0602562-A1 | Process for the preparation of phthalocyanine reactive dyes | BASF Aktiengesellschaft (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0527441-A2 | Water-soluble phthalocyanine dyes, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0192964-B1 | PHTHALOCYANINE REACTIVE DYES | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0192964-A2 | Phthalocyanine reactive dyes | BAYER AG (DE) | 1986-09-03 | — | — | EP | disclosed |
| EP-0075905-B1 | WATER-SOLUBLE REACTIVE PHTHALOCYANINE COMPOUNDS; PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0075905-A2 | Water-soluble reactive phthalocyanine compounds; process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-06 | — | — | EP | disclosed |