Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20732371 | 0.92 | PTGS1 (0.44) | PTGS1PTGS2CA1CA2FAAH | |
| SCHEMBL16006806 | 0.90 | PTGS1 (0.44) | PTGS1PTGS2FAAHMGLLALDH1A1 | |
| SCHEMBL16006820 | 0.89 | PTGS1 (0.44) | PTGS1PTGS2FAAHMGLLHDAC3 | |
| SCHEMBL16006863 | 0.83 | PTGS1 (0.54) | PTGS1PTGS2FAAHMGLLALDH1A1 | |
| SCHEMBL27175515 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2FAAHMGLLALDH1A1 | |
| SCHEMBL19901568 | 0.83 | PTGS1 (0.40) | PTGS1PTGS2FAAHMGLLHDAC3 | |
| SCHEMBL17347440 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2FAAHMGLLHDAC3 | |
| SCHEMBL16006816 | 0.83 | SMN1; SMN2 (0.49) | PTGS1PTGS2ALDH1A1HTTMAPT | |
| SCHEMBL16006865 | 0.83 | TERT (0.39) | PTGS1PTGS2CA1CA2FAAH | |
| SCHEMBL17860045 | 0.82 | PTGS1 (0.42) | PTGS1PTGS2FAAHMGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014134486-A2 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN, INC. (US) | 2014-09-04 | — | — | WO | disclosed |