Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.32 |
| ▸ | KDM5A | P29375 | 3/20 | 0.32 |
| ▸ | KDM5C | P41229 | 3/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764334 | 0.78 | KDM4E (0.49) | KDM4ELMNA | |
| SCHEMBL321696 | 0.78 | CYP1A2 (0.44) | KDM4ELMNA | |
| Iodide SCHEMBL27088326 | 0.76 | CYP1A2 (0.43) | KDM4ELMNA | |
| Bromide SCHEMBL28155749 | 0.76 | CYP1A2 (0.43) | KDM4ELMNA | |
| SCHEMBL9764204 | 0.76 | LMNA (0.39) | KDM5BKDM5AKDM4EKDM4CLMNA | |
| SCHEMBL3696387 | 0.73 | KCNH2 (0.43) | KDM4ELMNA | |
| SCHEMBL28167678 | 0.73 | KCNH2 (0.43) | KDM4ELMNA | |
| SCHEMBL28290080 | 0.73 | KCNH2 (0.43) | KDM4ELMNA | |
| SCHEMBL24258324 | 0.72 | SIRT2 (0.43) | SIRT2SCN8A | |
| SCHEMBL15104622 | 0.72 | SIRT2 (0.45) | SIRT2CHRM2KDM5BKDM5CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014131777-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS APS (DK) | 2014-09-04 | — | — | WO | disclosed |