SCHEMBL160076

SCHEMBL160076

CC(SSC[C@H](N)C(=O)O)[C@H](N)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.42
NOS2 P35228 3/20 0.41
NOS1 P29475 2/20 0.41
NOS3 P29474 1/20 0.41
SLC1A3 P43003 3/20 0.38
SLC1A2 P43004 3/20 0.38
SLC1A1 P43005 2/20 0.38
KIF11 P52732 5/20 0.38
ARG1 P05089 1/20 0.38
ARG2 P78540 1/20 0.38
BHMT Q93088 2/20 0.37
BHMT2 Q9H2M3 1/20 0.37
GLO1 Q04760 1/20 0.36
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28326099 1.00 SLC7A5 (0.42) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL24068585 0.85 SLC7A5 (0.42) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL15539708 0.82 SLC7A5 (0.46) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL11680891 0.82 SLC7A5 (0.46) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL476398 0.80 SLC7A5 (0.45) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL2032831 0.80 SLC7A5 (0.45) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL360210 0.80 SLC7A5 (0.45) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL360209 0.80 SLC7A5 (0.45) SLC7A5NOS2NOS1NOS3SLC1A3
Cystine SCHEMBL28360714 0.80 SLC7A5 (0.62) SLC7A5NOS2NOS1NOS3SLC1A3
SCHEMBL11313182 0.80 ARG1 (0.40) SLC7A5NOS2NOS1NOS3SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269722-B Ergothioneine, S-methyl-ergothioneine and uses thereof 贝尔维奇生物医学研究所(伊迪贝尔) 2024-11-22 CN claimed
CN-114907546-B Multifunctional polyurea acid ester derivative and preparation method and application thereof 四川大学 2023-06-02 CN claimed
CN-114269722-A Ergothioneine, S-methyl-ergothioneine and uses thereof 贝尔维奇生物医学研究所(伊迪贝尔) 2022-04-01 CN claimed
CN-114269722-B Ergothioneine, S-methyl-ergothioneine and uses thereof 贝尔维奇生物医学研究所(伊迪贝尔) 2024-11-22 CN disclosed
CN-118613588-A SERPINA modulating compositions and methods 旗舰先锋创新VI有限责任公司 2024-09-06 CN disclosed
CN-118556123-A HBB modulating compositions and methods 旗舰先锋创新VI有限责任公司 2024-08-27 CN disclosed
CN-118489007-A Methods and compositions for modulating genome 旗舰先锋创新VI有限责任公司 2024-08-13 CN disclosed
CN-118318041-A Trans-recruitment of gene editing system components 旗舰先锋创新VI有限责任公司 2024-07-09 CN disclosed
CN-118318037-A Methods and compositions for modulating genome 旗舰先锋创新VI有限责任公司 2024-07-09 CN disclosed
CN-118109826-A Environment-friendly steel rust removing liquid and application thereof 江苏成泰高科有限公司 2024-05-31 CN disclosed
CN-116490610-A Methods and compositions for modulating genome 旗舰先锋创新VI有限责任公司 2023-07-25 CN disclosed
US-20030180804-A1 Solid phase synthesis of chemical libraries CORVAS INTERNATIONAL, INC 2003-09-25 US disclosed
CN-1424878-A Snack with improved flavor PROCTER & GAMBLE (US) 2003-06-18 CN disclosed
WO-2003040153-A1 PROCESS FOR PREPARING SILYLORGANOMERCAPTANS GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO disclosed
WO-2003037326-A1 SOLID PHASE SYNTHESIS OF CHEMICAL LIBRARIES CORVAS INTERNATIONAL, INC. (US) 2003-05-08 WO disclosed
US-6433206-B1 CLEAVAGE OF SULFUR-SULFUR BOND CROMPTON CORPORATION 2002-08-13 US disclosed
EP-0654041-B1 PEPTIDYL 4-AMINO-2,2-DIFLUORO-3-OXO-1,6-HEXANEDIOIC ACID DERIVATIVES AS ANTIINFLAMMATORY AGENTS PFIZER (US) 1998-07-01 EP disclosed
US-5739279-A Peptidyl 4-amino-2,2-difluoro-3-oxo-1,6-hexanedioic acid derivatives as antiinflammatory agents PFIZER INC. (US) 1998-04-14 US disclosed
EP-0654041-A1 PEPTIDYL 4-AMINO-2,2-DIFLUORO-3-OXO-1,6-HEXANEDIOIC ACID DERIVATIVES AS ANTIINFLAMMATORY AGENTS PFIZER INC. (US) 1995-05-24 EP disclosed
WO-1994003480-A1 PEPTIDYL 4-AMINO-2,2-DIFLUORO-3-OXO-1,6-HEXANEDIOIC ACID DERIVATIVES AS ANTIINFLAMMATORY AGENTS PFIZER INC. (US) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180804-A1 Solid phase synthesis of chemical libraries PEPD, DNPEP, PRSS1 SLC7A5 905/4885NOS2 1951/4885NOS1 2126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.