Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 16/20 | 0.64 |
| ▸ | CA1 | P00915 | 16/20 | 0.64 |
| ▸ | CA2 | P00918 | 16/20 | 0.64 |
| ▸ | CA9 | Q16790 | 16/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616952 | 0.88 | CA12 (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4616950 | 0.88 | CA12 (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL16009284 | 0.87 | CA12 (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL13903999 | 0.86 | CA12 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL13480225 | 0.86 | CA12 (0.67) | CA12CA1CA2CA9CA14 | |
| SCHEMBL13163929 | 0.86 | CA12 (0.67) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3267262 | 0.86 | CA12 (0.67) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7151935 | 0.86 | CA12 (0.67) | CA12CA1CA2CA9CA14 | |
| SCHEMBL7151688 | 0.86 | CA12 (0.67) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8763428 | 0.86 | CA12 (0.67) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085598-B2 | Compounds targeting the cell invasion protein complex, their pharmaceutical compositions and methods of use thereof | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2015-07-21 | — | — | US | disclosed |
| US-20140256659-A1 | Compounds Targeting the Cell Invasion Protein Complex, Their Pharmaceutical Compositions and Methods of Use Thereof | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256659-A1 | Compounds Targeting the Cell Invasion Protein Complex, Their Pharmaceutical Compositions and Methods of Use Thereof | PTK2, ILK, CTTN | CA12 2331/4885CA1 1861/4885CA2 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.