SCHEMBL1600928

SCHEMBL1600928

CCCCCCS(=O)(=O)Nc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cn1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCD O00767 14/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1600483 0.99 SCD (0.61) SCD
SCHEMBL1600566 0.88 SCD (0.63) SCD
SCHEMBL1601058 0.84 SCD (0.65) SCD
SCHEMBL1601631 0.83 SCD (0.63) SCD
SCHEMBL1095845 0.83 SCD (0.57) SCD
SCHEMBL1601199 0.82 SCD (0.57) SCD
SCHEMBL1600782 0.82 SCD (0.71) SCD
SCHEMBL1600530 0.81 SCD (0.67) SCD
SCHEMBL1599947 0.79 SCD (0.81) SCD
SCHEMBL1098036 0.79 SCD (0.56) SCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651605-B1 PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC (CA) 2012-05-02 EP claimed
EP-1846035-B1 COMBINATION THERAPY XENON PHARMACEUTICALS INC (CA) 2011-09-21 EP claimed
EP-1846035-B1 COMBINATION THERAPY XENON PHARMACEUTICALS INC (CA) 2011-09-21 EP disclosed
US-7919484-B2 Combination therapy XENON PHARMACEUTICALS INC. (CA) 2011-04-05 US disclosed