Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1601058 | 0.99 | SCD (0.65) | SCDMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL1601034 | 0.89 | SCD (0.65) | SCDSMN1; SMN2WNT3A | |
| SCHEMBL1600782 | 0.88 | SCD (0.71) | SCD | |
| SCHEMBL1600530 | 0.87 | SCD (0.67) | SCD | |
| SCHEMBL1601596 | 0.86 | SCD (0.67) | SCDLMNAWNT3A | |
| SCHEMBL1600545 | 0.86 | SCD (0.57) | SCDSMN1; SMN2WNT3A | |
| SCHEMBL939097 | 0.85 | SCD (0.67) | SCD | |
| SCHEMBL1601883 | 0.84 | SCD (0.59) | SCDSMN1; SMN2WNT3A | |
| SCHEMBL1600483 | 0.84 | SCD (0.61) | SCD | |
| SCHEMBL1600928 | 0.83 | SCD (0.63) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651605-B1 | PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2012-05-02 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | disclosed |
| US-7919484-B2 | Combination therapy | XENON PHARMACEUTICALS INC. (CA) | 2011-04-05 | — | — | US | disclosed |