SCHEMBL160098

SCHEMBL160098

COC(=O)c1c(O)ccc(O)c1C(=O)OC

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.77
CA1 P00915 8/20 0.77
CA2 P00918 8/20 0.77
CA7 P43166 8/20 0.77
CA9 Q16790 8/20 0.77
CA14 Q9ULX7 8/20 0.77
KDM4E B2RXH2 3/20 0.61
HSD17B10 Q99714 2/20 0.61
XDH P47989 2/20 0.56
LMNA P02545 3/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 2/20 0.52
ACHE P22303 1/20 0.52
HPGD P15428 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10882360 0.89 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL17926325 0.89 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL161350 0.88 CA12 (0.68) CA12CA1CA2CA7CA9
SCHEMBL1519936 0.87 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL18978962 0.87 HSD17B10 (0.65) CA12CA1CA2CA7CA9
SCHEMBL19052254 0.85 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL19052255 0.84 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL20778162 0.83 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL1538272 0.83 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL15563253 0.83 CA12 (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2659037-B1 CARPETS PREPARED FROM YARNS COMPRISING A FLUORINATED POLYESTER BLEND DU PONT (US) 2017-07-26 EP disclosed
EP-2659040-B1 A FABRIC PREPARED FROM FLUORINATED POLYESTER BLEND YARNS DU PONT (US) 2017-03-01 EP disclosed
EP-2658923-B1 FLUORINATED POLYESTER BLEND DU PONT (US) 2017-02-01 EP disclosed
EP-2659036-B1 FIBERS AND YARNS FROM A FLUORINATED POLYESTER BLEND DU PONT (US) 2015-07-29 EP disclosed
US-9017788-B2 Carpets prepared from yarns comprising a fluorinated polyester blend E I DU PONT DE NEMOURS AND COMPANY (US) 2015-04-28 US disclosed
CN-103298883-B Fluorinated polyester blend DU PONT 2015-04-22 CN disclosed
US-8889256-B2 Fabric prepared from fluorinated polyester blend yarns E I DU PONT DE NEMOURS AND COMPANY (US) 2014-11-18 US disclosed
CN-102575029-B Polyester film with improved oil repellency E. I. DU PONT DE NEMOURS AND CO. (US) 2014-10-15 CN disclosed
US-8791212-B2 Fluorinated block copolyesters E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-29 US disclosed
US-8785568-B2 Polymer blend comprising fluorinated block copolyester E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-22 US disclosed
US-20110218317-A1 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218319-A1 POLYARAMID FILMS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218353-A1 FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110218316-A1 POLYESTER FILMS WITH IMPROVED OIL REPELLENCY E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-08 US disclosed
US-20110213118-A1 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-01 US disclosed
WO-2011028791-A2 POLYARAMID COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028778-A2 POLYESTERS COMPRISING FLUOROVINYLETHER FUNCTIONALIZED AROMATIC MOIETIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028771-A2 POLYESTER FILMS WITH IMPROVED OIL REPELLENCY E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
WO-2011028767-A2 FLUOROETHER FUNCTIONALIZED AROMATIC DIESTERS AND DERIVATIVES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-10 WO disclosed
US-5166208-A Antitumor agents; antibiotics BOSTON COLLEGE (US) 1992-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110218353-A1 FLUOROVINYL ETHER FUNCTIONALIZED AROMATIC DIESTERS, DERIVATIVES THEREOF, AND PROCESS FOR THE PREPARATION THEREOF PFAS, PAH, AFF4 CA12 4233/4885CA1 4041/4885CA2 4015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.