Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.50 |
| ▸ | BRD4 | O60885 | 3/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PRLHR | P49683 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118565 | 0.75 | MTHFD2 (0.50) | PDE10A | |
| SCHEMBL18711328 | 0.74 | DPP4 (0.58) | KCNK3BRD4CREBBPMAPT | |
| SCHEMBL3119582 | 0.72 | PDE10A (0.54) | MAPTMTORPDE10A | |
| SCHEMBL2969795 | 0.71 | MAPK1 (0.77) | KCNK3BRD4CREBBPMAPK1EP300 | |
| Hydrochloric Acid SCHEMBL9659841 | 0.71 | BRD4 (0.53) | KCNK3BRD4CREBBPPRLHR | |
| SCHEMBL15315468 | 0.71 | TNKS2 (0.56) | ADORA3 | |
| SCHEMBL29411302 | 0.71 | TNKS2 (0.56) | ADORA3 | |
| SCHEMBL27013363 | 0.68 | MTOR (0.49) | MAPTMTORPDE10A | |
| SCHEMBL27042576 | 0.68 | DPP4 (0.44) | MAPK1 | |
| SCHEMBL30613768 | 0.68 | MAPK1 (0.45) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140255426-A1 | WNT PATHWAY INHIBITORS FOR TREATING VIRAL INFECTIONS | EMORY UNIVERSITY (US) | 2014-09-11 | — | — | US | disclosed |