SCHEMBL16010978

SCHEMBL16010978

Nc1cccc(Nc2nc(Nc3cccc(N)c3)nc(N(Cc3ccccc3)Cc3ccccc3)n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
MEN1 O00255 3/20 0.49
GAA P10253 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 2/20 0.49
GFER P55789 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
FCGR3B O75015 1/20 0.46
FCGR1A P12314 1/20 0.46
FCGR2A P12318 1/20 0.46
CRHR1 P34998 4/20 0.44
KCNH3 Q9ULD8 1/20 0.43
POLB P06746 1/20 0.43
XBP1 P17861 1/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SYK P43405 1/20 0.43
ALDH1A1 P00352 1/20 0.41
IDH2 P48735 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30562898 1.00 MAPT (0.49) MAPTMEN1GAAKMT2ALMNA
SCHEMBL25381533 0.87 BCL6 (0.46) MAPTMEN1GAAKMT2ALMNA
SCHEMBL14118021 0.85 KCNH3 (0.46) MAPTMEN1GAAKMT2AKDM4E
SCHEMBL31149854 0.82 CFTR (0.53) MAPTMEN1GAAKMT2ALMNA
SCHEMBL16010929 0.82 CFTR (0.53) MAPTMEN1GAAKMT2ALMNA
SCHEMBL30562985 0.81 MEN1 (0.74) MAPTMEN1GAAKMT2ALMNA
SCHEMBL14236870 0.81 MEN1 (0.74) MAPTMEN1GAAKMT2ALMNA
SCHEMBL13921801 0.80 KCNH3 (0.69) MAPTMEN1GAAKMT2ALMNA
SCHEMBL30562940 0.80 KCNH3 (0.69) MAPTMEN1GAAKMT2ALMNA
SCHEMBL13917172 0.80 KCNH3 (0.69) MAPTMEN1GAAKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163218-A1 POLYIMIDE PRECURSOR FOR DISPLAY SUBSTRATE, POLYIMIDE FILM FOR DISPLAY SUBSTRATE, AND DISPLAY SUBSTRATE UBE CORPORATION (JP) 2025-05-22 US disclosed
US-10174166-B2 Polyimide precursor, polyimide, varnish, polyimide film, and substrate UBE INDUSTRIES, LTD. (JP) 2019-01-08 US disclosed
US-9511565-B2 Polyimide precursor, polyimide, polyimide film, and method for manufacturing triazine compound used for manufacturing same UBE INDUSTRIES, LTD. (JP) 2016-12-06 US disclosed
US-20150361222-A1 POLYIMIDE PRECURSOR, POLYIMIDE, VARNISH, POLYIMIDE FILM, AND SUBSTRATE UBE CORPORATION (JP) 2015-12-17 US disclosed
US-20140255710-A1 POLYIMIDE PRECURSOR, POLYIMIDE, POLYIMIDE FILM, AND METHOD FOR MANUFACTURING TRIAZINE COMPOUND USED FOR MANUFACTURING SAME NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140255710-A1 POLYIMIDE PRECURSOR, POLYIMIDE, POLYIMIDE FILM, AND METHOD FOR MANUFACTURING TRIAZINE COMPOUND USED FOR MANUFACTURING SAME F12, TERB1, PBRM1 MAPT 347/4885MEN1 601/4885GAA 3468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.