Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899247 | 1.00 | TLR8 (0.40) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL2190590 | 1.00 | TLR8 (0.40) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL16011046 | 1.00 | TLR8 (0.40) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL27831058 | 0.92 | CYP1A2 (0.41) | TLR8MEN1KMT2ATSHRCNR2 | |
| SCHEMBL16023274 | 0.92 | ESR1 (0.39) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL16023270 | 0.92 | ESR1 (0.39) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL16023271 | 0.92 | ESR1 (0.39) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL16023268 | 0.92 | ESR1 (0.39) | TLR8MAPTMEN1NR1I2LMNA | |
| SCHEMBL13620055 | 0.90 | THRA (0.40) | LMNASMPD1THRBNPSR1S1PR3 | |
| SCHEMBL3236127 | 0.84 | NR5A1 (0.49) | NR5A1TSHRCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256894-A1 | DIFLUORO BENZOTRIAZOLYL ORGANIC SEMICONDUCTOR MATERIAL, PREPARATION METHOD AND USE THEREOF | OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2014-09-11 | — | — | US | disclosed |