Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.63 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.63 |
| ▸ | RPS17 | P08708 | 1/20 | 0.63 |
| ▸ | RPSA | P08865 | 1/20 | 0.63 |
| ▸ | RPS2 | P15880 | 1/20 | 0.63 |
| ▸ | RPL35A | P18077 | 1/20 | 0.63 |
| ▸ | RPL7 | P18124 | 1/20 | 0.63 |
| ▸ | RPL17 | P18621 | 1/20 | 0.63 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.63 |
| ▸ | RPS3 | P23396 | 1/20 | 0.63 |
| ▸ | RPS12 | P25398 | 1/20 | 0.63 |
| ▸ | RPL13 | P26373 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011502 | 0.96 | CYP3A4 (0.69) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16009977 | 0.87 | CYP3A4 (0.72) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16011473 | 0.87 | CYP3A4 (0.91) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL4744337 | 0.87 | CYP3A4 (0.72) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL12850350 | 0.87 | CYP3A4 (0.72) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL16093313 | 0.85 | LMNA (0.74) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6424822 | 0.85 | CYP3A4 (0.77) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2321619 | 0.85 | CYP3A4 (0.77) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11043104 | 0.84 | CYP3A4 (0.69) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL18548827 | 0.83 | LMNA (0.71) | CYP3A4LMNATSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964268-A1 | ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2016-01-13 | — | — | EP | claimed |
| WO-2014138403-A1 | ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2014-09-12 | — | — | WO | claimed |
| EP-2964268-A1 | ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014138403-A1 | ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2014-09-12 | — | — | WO | disclosed |