Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16012 | 1.00 | GRIK1 (0.46) | GRIK1CYP2D6CYP2C19BLMGRIK2 | |
| SCHEMBL10729549 | 0.80 | GRIK1 (0.31) | GRIK1 | |
| SCHEMBL23252 | 0.78 | GRIK1 (0.47) | GRIK1CYP2D6CYP2C19GRIK2RNPEP | |
| SCHEMBL23250 | 0.78 | GRIK1 (0.47) | GRIK1CYP2D6CYP2C19GRIK2RNPEP | |
| SCHEMBL8617091 | 0.76 | GRIK1 (0.46) | GRIK1CYP2D6CYP2C19GRIK2RNPEP | |
| Hydrochloric Acid SCHEMBL38657492 | 0.76 | GRIK1 (0.46) | GRIK1CYP2D6CYP2C19GRIK2RNPEP | |
| Ammonia Solution, Strong SCHEMBL27781946 | 0.76 | GRIK1 (0.46) | GRIK1CYP2D6CYP2C19GRIK2RNPEP | |
| SCHEMBL669944 | 0.75 | GRIK1 (0.48) | GRIK1CYP2D6CYP2C19RNPEPSLC7A5 | |
| SCHEMBL4078788 | 0.75 | GRIK1 (0.48) | GRIK1CYP2D6CYP2C19RNPEPSLC7A5 | |
| SCHEMBL1409891 | 0.75 | GRIK1 (0.48) | GRIK1CYP2D6CYP2C19GRIK2RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025861-A1 | PROCESS FOR THE PREPARATION OF ( S ) - 3 - CYANO - 5 - METHYLHEXANOIC ACID DERIVATIVES ADN OF PREGABALIN | PFIZER MANUFACTURING IRELAND (IE) | 2012-03-01 | — | — | WO | disclosed |