Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.35 |
| ▸ | CA1 | P00915 | 12/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 8/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407515 | 0.93 | CA2 (0.44) | CA2CA1TSHR | |
| SCHEMBL9543126 | 0.88 | CA1 (0.41) | CA2CA1USP2TSHRKDM4E | |
| SCHEMBL30164353 | 0.85 | CA1 (0.39) | CA2CA1USP2TSHRKDM4E | |
| SCHEMBL25989148 | 0.84 | TSHR (0.46) | CA2CA1USP2TSHRKDM4E | |
| SCHEMBL16116335 | 0.82 | CA2 (0.36) | CA2CA1TSHRALDH1A1CA9 | |
| SCHEMBL30671863 | 0.80 | CA2 (0.35) | CA2 | |
| SCHEMBL14444719 | 0.78 | USP2 (0.57) | CA2CA1USP2TSHRKDM4E | |
| SCHEMBL9647721 | 0.77 | USP2 (0.37) | CA2CA1USP2TSHRKDM4E | |
| SCHEMBL776569 | 0.77 | — | — | |
| SCHEMBL575454 | 0.77 | TSHR (0.48) | CA2CA1USP2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532228-A | 2'-O-(2-methoxyethyl)adenosine and 2'-O-(2-methoxyethyl)guanosine, preparation of derivatives thereof and purifying methods thereof | HONGENE BIOTECHNOLOGY LTD | 2012-07-04 | — | — | CN | claimed |
| EP-2964635-A1 | ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2016-01-13 | — | — | EP | disclosed |
| CN-102532228-B | The preparation of 2 '-O-(2-methoxyethyl) adenosine and 2 '-O-(2-methoxyethyl) guanosine and derivative thereof and purification process thereof | Hongene Biotechnology Limited (CN) | 2016-01-06 | — | — | CN | disclosed |
| WO-2014135495-A1 | ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-09-12 | — | — | WO | disclosed |
| CN-102532228-A | 2'-O-(2-methoxyethyl)adenosine and 2'-O-(2-methoxyethyl)guanosine, preparation of derivatives thereof and purifying methods thereof | HONGENE BIOTECHNOLOGY LTD | 2012-07-04 | — | — | CN | disclosed |