⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL2312528 | 0.86 | — | — | |
| Pyridine SCHEMBL693724 | 0.86 | — | — | |
| Pyridine SCHEMBL4450560 | 0.83 | — | — | |
| Pyridine SCHEMBL11056195 | 0.83 | — | — | |
| Pyridine SCHEMBL11056192 | 0.83 | — | — | |
| Pyridine SCHEMBL2141920 | 0.83 | — | — | |
| Pyridine SCHEMBL4450558 | 0.83 | — | — | |
| Pyridine SCHEMBL16702934 | 0.73 | TP53 (0.30) | — | |
| Pyridine SCHEMBL1736019 | 0.73 | TP53 (0.30) | — | |
| Pyridine SCHEMBL31757303 | 0.73 | TP53 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207432-B2 | Substituted organofluoroborates as imaging agents | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-12-28 | — | — | US | disclosed |
| US-20200222563-A1 | SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-07-16 | — | — | US | disclosed |
| US-10556023-B2 | Substituted organofluoroborates as imaging agents | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-02-11 | — | — | US | disclosed |
| US-20160038619-A1 | SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-02-11 | — | — | US | disclosed |
| EP-2964658-A1 | SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS | The University Of British Columbia (CA) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014134716-A9 | SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-11-20 | — | — | WO | disclosed |
| WO-2014134716-A1 | SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2014-09-12 | — | — | WO | disclosed |