Pyridine

Pyridine

SCHEMBL1736019

[O-2].c1cc[nH+]cc1.c1cc[nH+]cc1

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL10965108 0.95
Pyridine SCHEMBL30336469 0.95
Pyridine SCHEMBL30320033 0.90 TP53 (0.30) TP53TSHR
Pyridine SCHEMBL31579081 0.90
Pyridine SCHEMBL30718930 0.90
Pyridine SCHEMBL29384311 0.90
Pyridine SCHEMBL16702934 0.90 TP53 (0.30) TP53TSHR
Pyridine SCHEMBL31757303 0.90 TP53 (0.30) TP53TSHR
Pyridine SCHEMBL11087275 0.90 TP53 (0.30) TP53TSHR
Pyridine SCHEMBL9622112 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111875581-A Indolylpyridine oxide salt with novel structure and preparation method and application thereof 河南大学 2020-11-03 CN disclosed
US-9133128-B2 Pyrazole derivatives as cannabinoid receptor 1 antagonists RESEARCH TRIANGLE INSTITUTE (US) 2015-09-15 US disclosed
US-20140107157-A1 PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR 1 ANTAGONISTS RESEARCH TRIANGLE INSTITUTE (US) 2014-04-17 US disclosed
WO-2012174362-A1 PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR 1 ANTAGONISTS RESEARCH TRIANGLE INSTITUTE (US) 2012-12-20 WO disclosed
EP-2399885-A1 Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification Dietz, Ulrich (DE) 2011-12-28 EP disclosed
US-20080234271-A1 Arylphenylamino- and Arylphenylether-Sulfide Derivatives, Useful For the Treatment of Inflammatory and Immune Diseases, and Pharmaceutical Compositions Containing Them ICOS CORPORATION (US) 2008-09-25 US disclosed
US-20070259863-A1 Arylphenylamino-,Arylphenylamide-, and Arylphenylether-Sulfide Derivatives ICOS CORPORATION (US) 2007-11-08 US disclosed
US-20070066585-A1 ARYL PHENYLHETEROCYCLYL SULFIDE DERIVATIVES AND THEIR USE AS CELL ADHESION-INHIBITING ANTI-INFLAMMATORY AND IMMUNE-SUPPRESSIVE AGENTS WANG GARY T 2007-03-22 US disclosed
EP-1740561-A2 ARYLPHENYLAMINO-AND ARYLPHENYLETHER-SULFIDE DERIVATIVES, USEFUL FOR THE TREATMENT OF INFLAMMATORY AND IMMUNE DISEASES, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ICOS Corporation (US) 2007-01-10 EP disclosed
EP-1740565-A2 ARYLPHENYLAMINO-, ARYLPHENYLAMIDE-, AND ARYLPHENYLETHER-SUFIDE DERIVATIVES ICOS Corporation (US) 2007-01-10 EP disclosed
US-6013795-A Alpha-branched fluoroalkylcarbonyl fluorides and their derivatives 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-01-11 US disclosed
US-5998521-A CONTAINING A BRANCHED FLUOROALKYLCARBONYL COMPOUND AS EMULSIFIER 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-12-07 US disclosed
EP-0937027-A1 ALPHA-BRANCHED FLUOROALKYLCARBONYL FLUORIDES AND THEIR DERIVATIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-08-25 EP disclosed
EP-0935486-A1 AQUEOUS FILM-FORMING FOAM COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-08-18 EP disclosed
EP-0935621-A1 AQUEOUS FLUOROPOLYMER COMPOSITIONS AND METHOD OF PREPARING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-08-18 EP disclosed
WO-1998020055-A1 AQUEOUS FLUOROPOLYMER COMPOSITIONS AND METHOD OF PREPARING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-14 WO disclosed
WO-1998019988-A1 ALPHA-BRANCHED FLUOROALKYLCARBONYL FLUORIDES AND THEIR DERIVATIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-14 WO disclosed
WO-1998019742-A1 AQUEOUS FILM-FORMING FOAM COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-14 WO disclosed
EP-0075335-B1 PROCESS FOR THE CO-PRODUCTION OF CARBOXYLIC ACIDS AND CARBOXYLIC ACID ESTERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-10-23 EP disclosed
EP-0075335-A1 Process for the co-production of carboxylic acids and carboxylic acid esters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1983-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107157-A1 PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR 1 ANTAGONISTS CNR1, CNR2, GPR119 TP53 4461/4885TSHR 1253/4885
US-20070259863-A1 Arylphenylamino-,Arylphenylamide-, and Arylphenylether-Sulfide Derivatives AHR, ARSA, TST TP53 2271/4885TSHR 3012/4885
US-20080234271-A1 Arylphenylamino- and Arylphenylether-Sulfide Derivatives, Useful For the Treatment of Inflammatory and Immune Diseases, and Pharmaceutical Compositions Containing Them HPGDS, AHR, TST TP53 2424/4885TSHR 2954/4885
US-20070066585-A1 ARYL PHENYLHETEROCYCLYL SULFIDE DERIVATIVES AND THEIR USE AS CELL ADHESION-INHIBITING ANTI-INFLAMMATORY AND IMMUNE-SUPPRESSIVE AGENTS VCAM1, ICAM1, CD47 TP53 3533/4885TSHR 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.