SCHEMBL16015213

SCHEMBL16015213

COc1cc2ccc(=O)oc2c(C)c1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 8/20 0.77
CA12 O43570 7/20 0.77
CA1 P00915 7/20 0.77
CA7 P43166 7/20 0.77
CA13 Q8N1Q1 7/20 0.77
MCL1 Q07820 7/20 0.77
KDM4E B2RXH2 7/20 0.77
HSD17B10 Q99714 6/20 0.77
ALDH1A1 P00352 5/20 0.77
HPGD P15428 5/20 0.77
CASP1 P29466 3/20 0.77
CASP7 P55210 3/20 0.77
MEN1 O00255 3/20 0.77
KMT2A Q03164 3/20 0.77
SMN1; SMN2 Q16637 3/20 0.77
MAPT P10636 3/20 0.77
TDP1 Q9NUW8 3/20 0.77
CYP2C9 P11712 2/20 0.77
CYP2C19 P33261 2/20 0.77
ALOX15 P16050 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fraxetin SCHEMBL43472 0.87 CA9 (1.00) CA9CA12CA1CA7CA13
Fraxetin SCHEMBL30010613 0.87 CA9 (1.00) CA9CA12CA1CA7CA13
SCHEMBL14296936 0.86 CA9 (0.79) CA9CA12CA1CA7CA13
SCHEMBL30098746 0.84 CA9 (0.78) CA9CA12CA1CA7CA13
SCHEMBL3924718 0.84 CA9 (0.78) CA9CA12CA1CA7CA13
SCHEMBL29396102 0.81 CA9 (1.00) CA9CA12CA1CA7CA13
SCHEMBL3190311 0.81 CA9 (1.00) CA9CA12CA1CA7CA13
SCHEMBL14316132 0.81 CA9 (0.71) CA9CA12CA1CA7CA13
SCHEMBL14296929 0.81 KDM4E (0.71) CA9CA12CA1CA7CA13
SCHEMBL27987501 0.80 GAA (0.56) CA9CA12CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8828954-B2 Use for scopolin and derivatives thereof YONSEI UNIVERSITY TECHNOLOGY HOLDINGS, INC. (KR) 2014-09-09 US disclosed