Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 9/20 | 1.00 |
| ▸ | CA12 | O43570 | 8/20 | 1.00 |
| ▸ | CA1 | P00915 | 8/20 | 1.00 |
| ▸ | CA7 | P43166 | 8/20 | 1.00 |
| ▸ | CA13 | Q8N1Q1 | 8/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.77 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | HPGD | P15428 | 5/20 | 0.77 |
| ▸ | CASP1 | P29466 | 3/20 | 0.77 |
| ▸ | CASP7 | P55210 | 3/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.77 |
| ▸ | CA2 | P00918 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396102 | 1.00 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| Methoxymethane SCHEMBL2253445 | 0.98 | CA9 (0.97) | CA9CA12CA1CA7CA13 | |
| SCHEMBL3924718 | 0.88 | CA9 (0.78) | CA9CA12CA1CA7CA13 | |
| SCHEMBL30098746 | 0.88 | CA9 (0.78) | CA9CA12CA1CA7CA13 | |
| Fraxetin SCHEMBL43472 | 0.87 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| SCHEMBL4659463 | 0.87 | CA9 (0.77) | CA9CA12CA1CA7CA13 | |
| Fraxetin SCHEMBL30010613 | 0.87 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| SCHEMBL30152059 | 0.86 | CA9 (0.75) | CA9CA12CA1CA7CA13 | |
| Fraxidin Methyl Ether SCHEMBL2464275 | 0.85 | CA9 (1.00) | CA9CA12CA1CA7CA13 | |
| SCHEMBL14296936 | 0.83 | CA9 (0.79) | CA9CA12CA1CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119752834-A | Oxygen methyl transferase and application thereof in biosynthesis of isofraxidin and fraxidin | 中国农业科学院深圳农业基因组研究所(岭南现代农业科学与技术广东省实验室深圳分中心) | 2025-04-04 | — | — | CN | claimed |
| CN-114306231-B | Flurara pesticide and preparation method and application thereof | 天津市中升挑战生物科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-115778969-A | Application of aesculin and analogs thereof in preparation of coronavirus 3CL protease inhibitor | 陕西科技大学 | 2023-03-14 | — | — | CN | claimed |
| CN-115778943-A | Application of fraxins in resisting coronavirus | 上海科技大学 | 2023-03-14 | — | — | CN | claimed |
| CN-115785015-A | Synthetic method of sodium fluridide | 天和药业股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115671288-A | Antiparasitic compound soft chewable medicinal preparation and preparation method and application thereof | 瑞普（天津）生物药业有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115594645-A | Synthesis method of flurarana | 世华合创生物技术开发（山东）有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-113117657-B | Preparation and application of beta-cyclodextrin metal organic framework material HPLC column | 中南民族大学 | 2022-12-13 | — | — | CN | claimed |
| CN-111529683-B | Application of polypeptide ABC transporter inhibitor | 湖南科技学院 | 2022-10-11 | — | — | CN | claimed |
| CN-111701009-B | Polypeptide ABC transporter inhibitor XH-14C and application thereof | 湖南科技学院 | 2022-10-11 | — | — | CN | claimed |
| CN-112707809-A | Method for preparing oxazoline insecticide frainer intermediate | 丽珠集团新北江制药股份有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-112656788-A | Traditional Chinese medicine effective component for treating eye diseases and composition thereof | 上海中医药大学 | 2021-04-16 | — | — | CN | claimed |
| CN-111759802-A | Compound fraxidin suspension and preparation and application thereof | 天津市中升挑战生物科技有限公司 | 2020-10-13 | — | — | CN | claimed |
| CN-111701009-A | Polypeptide ABC transporter inhibitor XH-14C and application thereof | 湖南科技学院 | 2020-09-25 | — | — | CN | claimed |
| CN-111689919-A | Synthetic method of isoxazoline anthelmintic | 天津市中升挑战生物科技有限公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111675667-A | Preparation method of isoxazoline anthelmintic | 天津市中升挑战生物科技有限公司 | 2020-09-18 | — | — | CN | claimed |
| CN-111529683-A | Application of polypeptide ABC transporter inhibitor | 湖南科技学院 | 2020-08-14 | — | — | CN | claimed |
| CN-111110671-A | Application of fraxins in resisting aquatic animal streptococcus agalactiae infection | 中国水产科学研究院长江水产研究所 | 2020-05-08 | — | — | CN | claimed |
| CN-110876741-A | GBE1 inhibitor frataxin and application of pharmaceutical composition thereof in preparation of drugs for treating lung adenocarcinoma | 郑州大学第一附属医院 | 2020-03-13 | — | — | CN | claimed |
| CN-110740751-A | Conjugates for the treatment of lung cancer | LDN制药有限公司 | 2020-01-31 | — | — | CN | claimed |