Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325537 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTHSD17B10TSHR | |
| SCHEMBL6323588 | 0.66 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTHSD17B10TSHR | |
| SCHEMBL1992335 | 0.64 | TRIM24 (0.40) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL131908 | 0.64 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL5464775 | 0.62 | TRIM24 (0.39) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL1702146 | 0.62 | — | — | |
| SCHEMBL6151244 | 0.62 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL8070883 | 0.62 | TRIM24 (0.38) | ALDH1A1HPGDMAPTHSD17B10HTT | |
| SCHEMBL19068482 | 0.62 | — | — | |
| SCHEMBL29540851 | 0.62 | TRIM24 (0.38) | ALDH1A1HPGDMAPTHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345708-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2016-05-24 | — | — | US | disclosed |
| US-8829007-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-09-09 | — | — | US | disclosed |