SCHEMBL16015441

SCHEMBL16015441

CC(C)=CCCCC(C)C1CCC2C3CC=C4C(C)(C)C(OC(=O)/C=C/c5ccc(OCOc6cc(N)cc(N)c6)cc5)CCC4(C)C3CCC12C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 3/20 0.43
PTPN1 P18031 7/20 0.39
EPHA2 P29317 2/20 0.39
NR1H3 Q13133 3/20 0.38
OSBP P22059 2/20 0.38
OSBP2 Q969R2 2/20 0.38
CRYAB P02511 1/20 0.38
HMGCR P04035 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGAV P06756 1/20 0.38
SREBF2 Q12772 1/20 0.38
NPC1L1 Q9UHC9 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
USP2 O75604 1/20 0.38
LMNA P02545 1/20 0.38
ABCB1 P08183 1/20 0.38
CYP46A1 Q9Y6A2 1/20 0.38
PTPN2 P17706 3/20 0.37
POLA1 P09884 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15503577 0.92 RORC (0.45) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL15503583 0.91 RORC (0.46) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL12587258 0.90 RORC (0.48) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL16015442 0.89 RORC (0.41) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL10017601 0.89 RORC (0.43) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL12587284 0.87 RORC (0.47) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL10017594 0.86 RORC (0.50) RORCPTPN1NR1H3OSBPOSBP2
SCHEMBL12172528 0.83 RORC (0.50) RORCPTPN1EPHA2NR1H3OSBP
SCHEMBL11999082 0.83 RORC (0.49) RORCPTPN1NR1H3OSBPOSBP2
SCHEMBL105665 0.82 RORC (0.55) RORCPTPN1EPHA2NR1H3OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8830428-B2 Liquid crystal display element and liquid crystal display device SONY CORPORATION (JP) 2014-09-09 US disclosed