Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062678 | 0.98 | ADORA2A (0.54) | ADORA1ADORA2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL13589943 | 0.86 | RXRA (0.42) | ADORA1ADORA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL18643833 | 0.84 | ADORA2A (0.51) | ADORA1ADORA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL20088882 | 0.84 | CYP1A2 (0.65) | CYP1A2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL18419157 | 0.84 | CYP1A2 (0.65) | CYP1A2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL23560521 | 0.84 | CYP1A2 (0.65) | ADORA1ADORA2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL16949645 | 0.84 | CYP1A2 (0.65) | CYP1A2ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL27471611 | 0.84 | RXRA (0.58) | ADORA1ADORA2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL12447715 | 0.83 | ADORA2A (0.50) | ADORA1ADORA2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL23789097 | 0.83 | AKR1C2 (0.47) | ADORA1ADORA2AHPGDL3MBTL1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361909-B1 | 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | TOSOH CORP (JP) | 2014-09-10 | — | — | EP | disclosed |