Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 5/20 | 0.35 |
| ▸ | BRAF | P15056 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16017253 | 0.90 | STIM1 (0.43) | SCN9ASTIM1ORAI1POLQIL2 | |
| SCHEMBL16018222 | 0.86 | STIM1 (0.53) | SCN9ASTIM1ORAI1POLQIL2 | |
| SCHEMBL17805358 | 0.85 | SMN1; SMN2 (0.51) | SCN9ANPSR1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL16017226 | 0.84 | SCN9A (0.45) | SCN9ASTIM1ORAI1POLQIL2 | |
| SCHEMBL14887583 | 0.84 | SCN9A (0.43) | SCN9ASTIM1ORAI1POLQIL2 | |
| SCHEMBL14881301 | 0.83 | MEN1 (0.53) | SCN9ASTIM1ORAI1IL2HTT | |
| SCHEMBL14887348 | 0.81 | SCN9A (0.43) | SCN9ASTIM1ORAI1POLQIL2 | |
| SCHEMBL16017274 | 0.81 | NPC1 (0.50) | SCN9ASTIM1ORAI1POLQIL2 | |
| SCHEMBL16017210 | 0.81 | MEN1 (0.50) | SCN9ARAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL14887562 | 0.80 | STIM1 (0.55) | SCN9ASTIM1ORAI1POLQIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | SCN9A 235/4885STIM1 17/4885ORAI1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.