Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16017330 | 0.92 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAHTTITGB1ITGA4 | |
| SCHEMBL16019860 | 0.92 | ITGB1 (0.41) | SMN1; SMN2LMNAEPHX2PPARGHDAC3 | |
| SCHEMBL16017293 | 0.89 | HTT (0.46) | SMN1; SMN2LMNAHTTEPHX2PPARG | |
| SCHEMBL16017268 | 0.89 | ITGB1 (0.50) | SMN1; SMN2HTTITGB1ITGA4TRPA1 | |
| SCHEMBL16017332 | 0.88 | LMNA (0.45) | SMN1; SMN2LMNAHTTHDAC1ITGB1 | |
| SCHEMBL14887744 | 0.87 | ITGB1 (0.52) | ITGB1ITGA4TRPA1GAAMEN1 | |
| SCHEMBL14887761 | 0.87 | HDAC3 (0.43) | SMN1; SMN2LMNAHTTEPHX2PPARG | |
| SCHEMBL16017315 | 0.84 | LMNA (0.42) | SMN1; SMN2LMNAHTTITGB1ITGA4 | |
| SCHEMBL16017306 | 0.82 | HTT (0.46) | SMN1; SMN2LMNAHTTTRPA1POLB | |
| SCHEMBL14887754 | 0.81 | LMNA (0.58) | SMN1; SMN2LMNAHTTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | SMN1; SMN2 854/4885LMNA 1306/4885HTT 809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.