Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14887755 | 0.91 | RAB9A (0.55) | RAB9AMAPTGAANPSR1ITGB1 | |
| SCHEMBL16017308 | 0.86 | TLR7 (0.46) | RAB9AMAPTGAANPSR1ITGB1 | |
| SCHEMBL16017324 | 0.84 | HTT (0.47) | RAB9AMAPTGAANPSR1IL2 | |
| SCHEMBL16019869 | 0.83 | ITGB1 (0.47) | RAB9AMAPTGAANPSR1ITGB1 | |
| SCHEMBL16019822 | 0.81 | IL2 (0.47) | RAB9AMAPTGAANPSR1IL2 | |
| SCHEMBL16017304 | 0.81 | ITGB1 (0.53) | RAB9AMAPTGAANPSR1ITGB1 | |
| SCHEMBL14887742 | 0.81 | MEN1 (0.65) | RAB9AMAPTTLR8MEN1KMT2A | |
| SCHEMBL14887756 | 0.81 | TYK2 (0.49) | RAB9AMAPTGAANPSR1IL2 | |
| SCHEMBL16017326 | 0.81 | GAA (0.52) | GAAITGB1ITGA4TLR7TLR8 | |
| SCHEMBL16017392 | 0.80 | ITGB1 (0.44) | RAB9AMAPTGAANPSR1ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2014-09-11 | — | — | US | disclosed |
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256771-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | RAB9A 1174/4885MAPT 1478/4885GAA 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.