SCHEMBL16017482

SCHEMBL16017482

c1ccc(-n2c3ccccc3c3cc4c5ccccc5n(-c5cccc(N6c7ccccc7[Si](c7ccccc7)(c7ccccc7)c7ccccc76)c5)c4cc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPK8 P45983 1/20 0.33
MAPK9 P45984 1/20 0.33
ALDH1A1 P00352 1/20 0.31
KDR P35968 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16008229 0.94 KDM4E (0.46) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL16017483 0.93 KDM4E (0.46) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL16017480 0.91 KDM4E (0.41) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL16017492 0.91 KDM4E (0.42) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL23809571 0.89 KDM4E (0.47) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL16008111 0.88 ATM (0.42) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL19764681 0.87 KDM4E (0.45) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL16017487 0.87 KDM4E (0.34) KDM4EATML3MBTL1
SCHEMBL16017494 0.86 ATM (0.42) KDM4EATML3MBTL1MAPK8MAPK9
SCHEMBL16017497 0.85 KDM4E (0.34) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed