SCHEMBL16008111

SCHEMBL16008111

c1ccc([Si]2(c3ccccc3)c3ccccc3N(c3cccc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)c3)c3ccccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 3/20 0.36
HTT P42858 2/20 0.36
FAAH O00519 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PKM P14618 1/20 0.36
MGLL Q99685 1/20 0.36
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
WNK1 Q9H4A3 1/20 0.31
CYP19A1 P11511 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16017479 0.94 ATM (0.43) ATML3MBTL1KDM4EALDH1A1HTT
SCHEMBL16008229 0.93 KDM4E (0.46) ATML3MBTL1KDM4EALDH1A1MAPK8
SCHEMBL16017494 0.93 ATM (0.42) ATML3MBTL1KDM4EALDH1A1HTT
SCHEMBL16017492 0.90 KDM4E (0.42) ATML3MBTL1KDM4EALDH1A1MAPK8
SCHEMBL19764681 0.90 KDM4E (0.45) ATML3MBTL1KDM4EALDH1A1MAPK8
SCHEMBL16017480 0.89 KDM4E (0.41) ATML3MBTL1KDM4EALDH1A1MAPK8
SCHEMBL20022914 0.88 ALDH1A1 (0.45) ATMALDH1A1HTTFAAHHSP90AA1
SCHEMBL16017482 0.88 KDM4E (0.44) ATML3MBTL1KDM4EALDH1A1MAPK8
SCHEMBL16865074 0.86 ATM (0.34) ATML3MBTL1KDM4EALDH1A1HTT
SCHEMBL16017498 0.86 ALDH1A1 (0.47) ATMALDH1A1HTTFAAHHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed