Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16843 | 1.00 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| SCHEMBL105348 | 1.00 | NR1H2 (0.47) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| Hydrochloric Acid SCHEMBL25337897 | 0.98 | NR1H2 (0.46) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| Piperazine SCHEMBL28853588 | 0.97 | NR1H2 (0.45) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| SCHEMBL28002373 | 0.97 | HPGD (0.48) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| Acetic Acid SCHEMBL28827133 | 0.95 | NR1H2 (0.44) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| Urea SCHEMBL4467391 | 0.95 | NR1H2 (0.44) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| Acetic Acid SCHEMBL28060582 | 0.95 | NR1H2 (0.44) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| SCHEMBL31540 | 0.90 | HPGD (0.48) | NR1H2USP2SMN1; SMN2MAPK1HPGD | |
| SCHEMBL2898103 | 0.90 | HPGD (0.48) | NR1H2USP2SMN1; SMN2MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2065 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234546-B1 | IMPROVED SYNTHESIS OF KEY INTERMEDIATE OF KRAS G12C INHIBITOR COMPOUND | AMGEN INC (US) | 2026-04-15 | — | — | EP | claimed |
| US-20250388579-A1 | SYNTHESIS OF KRAS G12C INHIBITOR COMPOUND | AMGEN INC. (US) | 2025-12-25 | — | — | US | claimed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| CN-117903117-A | Preparation method of KRAS G12C inhibitor divarasib | 云南万宏医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117624140-A | CXCR4 antagonists, methods of making and uses thereof | 杭州师范大学 | 2024-03-01 | — | — | CN | claimed |
| CN-115466259-B | Preparation method of KRAS G12C inhibitor sotorubin | 山东大学 | 2023-12-05 | — | — | CN | claimed |
| EP-4234546-A2 | IMPROVED SYNTHESIS OF KEY INTERMEDIATE OF KRAS G12C INHIBITOR COMPOUND | Amgen Inc. (US) | 2023-08-30 | — | — | EP | claimed |
| CN-115466259-A | Preparation method of KRAS G12C inhibitor sotoxib | 山东大学 | 2022-12-13 | — | — | CN | claimed |
| CN-114057654-A | Preparation method of (S) -1-Boc-3-methylpiperazine | 苏州艾缇克药物化学有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113754579-A | Preparation method of pyridine derivative | 正大天晴药业集团股份有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-111675700-A | Preparation method of novel anti-cancer drug AZD3759 | 通化师范学院 | 2020-09-18 | — | — | CN | claimed |
| CN-111662273-A | Preparation method of tyrosine kinase inhibitor AZD3759 | 通化师范学院 | 2020-09-15 | — | — | CN | claimed |
| CN-104046246-B | The chemical-mechanical planarization of tungsten-containing substrate | 气体产品与化学公司 | 2016-06-15 | — | — | CN | claimed |
| US-20140273458-A1 | Chemical Mechanical Planarization for Tungsten-Containing Substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-18 | — | — | US | claimed |
| EP-2779217-A2 | Chemical mechanical planarization for tungsten-containing substrates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-09-17 | — | — | EP | claimed |
| EP-4747258-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics, Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4747248-A1 | COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION | Institute of Cancer Research: Royal Cancer Hospital (The) (GB) | 2026-05-27 | — | — | EP | disclosed |
| EP-0061673-B1 | ISOQUINOLINESULFONYL DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4456757-A | MUSCLE RELAXANTS, VASODILATORS, HYPOTENSIVE AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0061673-A1 | Isoquinolinesulfonyl derivatives and process for the preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-10-06 | — | — | EP | disclosed |