SCHEMBL16018652

SCHEMBL16018652

C=CCOc1cc(C)c([C@@H]2O[C@H](CC)C[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)cc1Cc1cc2ccccc2s1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 4/20 0.33
SLC5A1 P13866 2/20 0.33
CHRNA7 P36544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16018603 0.89 SLC5A2 (0.41) SLC5A2SLC5A1CHRNA7
SCHEMBL16018673 0.89 SLC5A2 (0.41) SLC5A2SLC5A1CHRNA7
SCHEMBL16018671 0.88 CHRNA7 (0.33) SLC5A2SLC5A1CHRNA7
SCHEMBL16018604 0.87 CHRNA7 (0.36) SLC5A2SLC5A1CHRNA7
SCHEMBL16018640 0.86 CHRNA7 (0.35) SLC5A2SLC5A1CHRNA7
SCHEMBL16018661 0.85
SCHEMBL16018612 0.85 SLC5A2 (0.36) SLC5A2SLC5A1CHRNA7
SCHEMBL16656269 0.85 SLC5A2 (0.40) SLC5A2SLC5A1CHRNA7
SCHEMBL16018651 0.85 SLC5A2 (0.37) SLC5A2SLC5A1CHRNA7
SCHEMBL16018609 0.85 SLC5A2 (0.40) SLC5A2SLC5A1CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012412-B2 Dual SGLT1/SGLT2 inhibitors JANSSEN PHARMACEUTICA NV (BE) 2015-04-21 US disclosed
US-20140256657-A1 DUAL SGLT1/SGLT2 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256657-A1 DUAL SGLT1/SGLT2 INHIBITORS SLC5A1, SLC5A2, GLP1R SLC5A2 2/4885SLC5A1 1/4885CHRNA7 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.