SCHEMBL16019247

SCHEMBL16019247

C=CC(=O)OCCCOc1ccc2cc(C(=O)Oc3ccc(C(=O)Oc4ccc(CC)cc4)cc3OC)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.44
MAPT P10636 3/20 0.43
MEN1 O00255 4/20 0.41
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ADRB2 P07550 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CYP2D6 P10635 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD2 P14416 1/20 0.41
TSHR P16473 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
CHRM3 P20309 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16019248 0.93 KMT2A (0.44) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL15855597 0.91 MAPT (0.50) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL15858633 0.90 MAPT (0.48) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL15858610 0.90 MAPT (0.51) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL815927 0.89 MAPT (0.45) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL15858660 0.88 MAPT (0.51) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL16885059 0.88 KMT2A (0.52) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL815808 0.88 MAPT (0.46) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL15858687 0.87 MAPT (0.50) KMT2AMAPTMEN1CYP3A4TDP1
SCHEMBL15858683 0.87 MAPT (0.50) KMT2AMAPTMEN1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108142-A1 POLARIZED LUMINESCENT FILM DIC CORPORATION (JP) 2021-04-15 US disclosed
US-9469810-B2 Polymerizable liquid crystal composition and thin film using same DIC CORPORATION (JP) 2016-10-18 US disclosed
US-20140256896-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND THIN FILM USING SAME DIC CORPORATION (JP) 2014-09-11 US disclosed