SCHEMBL16019248

SCHEMBL16019248

C=CC(=O)OCCCOc1ccc2cc(C(=O)Oc3ccc(C(=O)Oc4ccc(C)cc4)cc3OC)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.44
MAPT P10636 4/20 0.42
MEN1 O00255 4/20 0.42
ALDH1A1 P00352 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA9 Q16790 1/20 0.39
TP53 P04637 1/20 0.39
THRB P10828 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CTNNB1 P35222 1/20 0.38
WNT3A P56704 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23227544 0.93 KMT2A (0.49) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL16019247 0.93 KMT2A (0.44) KMT2AMAPTMEN1SMN1; SMN2TDP1
SCHEMBL15867564 0.91 KMT2A (0.49) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL23227537 0.90 KMT2A (0.48) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL15869951 0.90 MAPT (0.48) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL815927 0.89 MAPT (0.45) KMT2AMAPTMEN1TDP1CA12
SCHEMBL23227549 0.89 PPARG (0.40) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL16885059 0.88 KMT2A (0.52) KMT2AMAPTMEN1SMN1; SMN2TDP1
SCHEMBL815808 0.88 MAPT (0.46) KMT2AMAPTMEN1ALDH1A1TDP1
SCHEMBL15867572 0.88 KMT2A (0.45) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108142-A1 POLARIZED LUMINESCENT FILM DIC CORPORATION (JP) 2021-04-15 US disclosed
US-20200264461-A1 LIGHT CONVERSION FILM AND IMAGE DISPLAY DEVICE DIC CORPORATION (JP) 2020-08-20 US disclosed
US-9469810-B2 Polymerizable liquid crystal composition and thin film using same DIC CORPORATION (JP) 2016-10-18 US disclosed
US-20140256896-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND THIN FILM USING SAME DIC CORPORATION (JP) 2014-09-11 US disclosed