Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | SNCA | P37840 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | APEX1 | P27695 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | ALPL | P05186 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.65 |
| ▸ | RAD52 | P43351 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21738186 | 0.90 | BACE1 (0.57) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL30350384 | 0.89 | PTGS1 (0.58) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL21588096 | 0.89 | PTGS1 (0.58) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL13507916 | 0.87 | KDM4E (0.65) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL5077079 | 0.87 | BACE1 (0.68) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL5077075 | 0.87 | BACE1 (0.68) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL14691546 | 0.85 | BACE1 (0.65) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL14701480 | 0.85 | BACE1 (0.65) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL30414325 | 0.85 | BACE1 (0.65) | BACE1KDM4EPTGS1HSD17B10SNCA | |
| SCHEMBL14701419 | 0.85 | BACE1 (0.65) | BACE1KDM4EPTGS1HSD17B10SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187448-B2 | Flavonoid compounds | CARDERO THERAPEUTICS, INC. (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140256741-A1 | FLAVONOID COMPOUNDS | CARDERO THERAPEUTICS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256741-A1 | FLAVONOID COMPOUNDS | FIS1, TFAM, MFN2 | BACE1 4428/4885KDM4E 1854/4885PTGS1 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.