Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.70 |
| ▸ | PI4KA | P42356 | 1/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.55 |
| ▸ | AMD1 | P17707 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | ATG7 | O95352 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.42 |
| ▸ | UBA7 | P41226 | 1/20 | 0.42 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.42 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | TARS1 | P26639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379161 | 1.00 | RXFP1 (0.70) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1800279 | 0.90 | RXFP1 (0.70) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12379249 | 0.90 | RXFP1 (0.86) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1798431 | 0.90 | RXFP1 (0.70) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2294735 | 0.90 | RXFP1 (0.70) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2292456 | 0.90 | RXFP1 (0.86) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1796531 | 0.89 | RXFP1 (0.69) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1796386 | 0.89 | RXFP1 (0.69) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20133912 | 0.84 | PI4KA (0.65) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16579246 | 0.84 | RXFP1 (0.58) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256668-A9 | SUBSTITUTED PYRROLO]2,3-D]PYRIMIDINES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256668-A9 | SUBSTITUTED PYRROLO]2,3-D]PYRIMIDINES | DPYD, CCND3, POLD3 | RXFP1 1137/4885PI4KA 1546/4885PI4K2B 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.