POLD3

DNA polymerase delta subunit 3 · Q15054 · POLD3 on Sugi Atlas →

0 patent compounds predicted against POLD3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to POLD3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A RCT of TNF and ENT in the Treatment of Long-term Prognosis With Hepatitis B-related HCC After Curative Resection PHASE3UNKNOWN
Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers PHASE1/PHASE2COMPLETED
Durvalumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer PHASE2COMPLETED
Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis PHASE2ACTIVE_NOT_RECRUITING
Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE) PHASE1/PHASE2NOT_YET_RECRUITING
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Danazol for Treatment of Cytopenias in Patients With Cirrhosis PHASE2RECRUITING
Epirubicin, Docetaxel, and Capecitabine in Treating Women With Stage IIIA or Stage IIIB Breast Cancer PHASE2COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome PHASE1COMPLETED
A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors PHASE1COMPLETED
Tabectedin to Treat Children and Adolescents With Cancer PHASE1COMPLETED
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors PHASE1COMPLETED
Spironolactone and XPB-1 Integrity in the TFIIH Complex nanENROLLING_BY_INVITATION
Prevalence of Germline Alterations in Actionable Genes in Endometrial Cancer nanNOT_YET_RECRUITING
REal Word aPpLicAtion of Molecular Based Endometrial Cancer Classification nanRECRUITING
Better Delineation of CDK13 Related Phenotype and Epigenetic Signature. nanUNKNOWN
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
Cohort of Tumors With POLE/D1 Mutation nanRECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk nanNOT_YET_RECRUITING
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients nanCOMPLETED
PErsonalized TReatment for Endometrial Carcinoma nanRECRUITING
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Plant Extracted Natural Compounds Impact on Stage IV Breast Cancer Survival Time and Remission. nanUNKNOWN
Investigation of Copy Number Variations and Genetic Variants in POI nanRECRUITING
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome) nanCOMPLETED
Choroid Plexus Dysfunction in Neurological Diseases nanRECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
S8814A Biomarkers in Predicting Outcome in Postmenopausal Women With Hormone Receptor-Positive, Node-Positive Breast Cancer Treated With Tamoxifen With or Without Cyclophosphamide, Doxorubicin, and Fluorouracil nanCOMPLETED
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma nanCOMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a POLD3 binder may also engage these)

ProteinNameSimilarity
Q9EQ28 0.997 Q9EQ28 →
Q5ZK28 0.996 Q5ZK28 →
P84798 0.989 P84798 →
Q5REG6 0.976 Q5REG6 →
O60934 0.976 O60934 →
Q4ADK7 0.976 Q4ADK7 →
Q5RCV3 0.975 Q5RCV3 →
Q9R207 0.975 Q9R207 →
LYAR Cell growth-regulating nucleolar protein 0.974 landscape →
Q6AYK5 0.974 Q6AYK5 →
Q9WTU0 0.973 Q9WTU0 →
D3ZTQ1 0.972 D3ZTQ1 →
Q53F19 0.972 Q53F19 →
Q9QXK2 0.972 Q9QXK2 →
Q7TN31 0.972 Q7TN31 →
A0JPQ7 0.972 A0JPQ7 →
O08587 0.972 O08587 →
Q8HXY9 0.971 Q8HXY9 →
P49140 0.971 P49140 →
P14629 0.971 P14629 →
Q8BZR9 0.971 Q8BZR9 →
ERCC5 DNA excision repair protein ERCC-5 0.971 landscape →
Q80U93 0.971 Q80U93 →
Q9JIL9 0.971 Q9JIL9 →
Q4R627 0.971 Q4R627 →
Q4R6F6 0.971 Q4R6F6 →
Q5F3Z9 0.971 Q5F3Z9 →
RAD18 E3 ubiquitin-protein ligase RAD18 0.971 landscape →
O88271 0.971 O88271 →
Q14241 0.970 Q14241 →